Research Paper (990)

  • Bile acid-containing lipid nanoparticles enhance extrahepatic mRNA delivery
    Bile acid-containing lipid nanoparticles enhance extrahepatic mRNA delivery

    Patel S.K.

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  • Improving susceptibility of neuroendocrine tumors to radionuclide therapies: personalized approaches towards complementary treatments
    Improving susceptibility of neuroendocrine tumors to radionuclide therapies: personalized approaches towards complementary treatments

    Richter S.

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  • Tumor-on-a-chip models combined with mini-tissues or organoids for engineering tumor tissues
    Tumor-on-a-chip models combined with mini-tissues or organoids for engineering tumor tissues

    Hwangbo H.

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  • In vivo nanoparticle-based T cell imaging can predict therapy response towards adoptive T cell therapy in experimental glioma
    In vivo nanoparticle-based T cell imaging can predict therapy response towards adoptive T cell therapy in experimental glioma

    Hunger J.

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  • Tat-NTS peptide protects neurons against cerebral ischemia-reperfusion injury via ANXA1 SUMOylation in microglia
    Tat-NTS peptide protects neurons against cerebral ischemia-reperfusion injury via ANXA1 SUMOylation in microglia

    Zhou H.

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  • E3 ubiquitin ligase TRIM21 targets TIF1? to regulate ?-catenin signaling in glioblastoma
    E3 ubiquitin ligase TRIM21 targets TIF1? to regulate ?-catenin signaling in glioblastoma

    Li Y.

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  • 3D autofluorescence imaging of hydronephrosis and renal anatomical structure using cryo-micro-optical sectioning tomography
    3D autofluorescence imaging of hydronephrosis and renal anatomical structure using cryo-micro-optical sectioning tomography

    Fan G.

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  • Metabolite Neu5Ac triggers SLC3A2 degradation promoting vascular endothelial ferroptosis and aggravates atherosclerosis progression in ApoE-/-mice
    Metabolite Neu5Ac triggers SLC3A2 degradation promoting vascular endothelial ferroptosis and aggravates atherosclerosis progression in ApoE-/-mice

    Xiang P.

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  • PET imaging of focused-ultrasound enhanced delivery of AAVs into the murine brain
    PET imaging of focused-ultrasound enhanced delivery of AAVs into the murine brain

    Ajenjo J.

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  • Engineered oncolytic bacteria HCS1 exerts high immune stimulation and safety profiles for cancer therapy
    Engineered oncolytic bacteria HCS1 exerts high immune stimulation and safety profiles for cancer therapy

    Sun Y.

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  • Application of Lung-Targeted Lipid Nanoparticle-delivered mRNA of soluble PD-L1 via SORT Technology in Acute Respiratory Distress Syndrome
    Application of Lung-Targeted Lipid Nanoparticle-delivered mRNA of soluble PD-L1 via SORT Technology in Acute Respiratory Distress Syndrome

    Sun H.

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  • 1?,25(OH)2D3 ameliorates insulin resistance by alleviating ?? T cell inflammation via enhancing fructose-1,6-bisphosphatase 1 expression
    1?,25(OH)2D3 ameliorates insulin resistance by alleviating ?? T cell inflammation via enhancing fructose-1,6-bisphosphatase 1 expression

    Li P.

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  • Nuclear translocation of thioredoxin-1 promotes colorectal cancer development via modulation of the IL-6/STAT3 signaling axis through interaction with STAT3
    Nuclear translocation of thioredoxin-1 promotes colorectal cancer development via modulation of the IL-6/STAT3 signaling axis through interaction with STAT3

    Wu A.

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  • Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine
    Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine

    Ertveldt T.

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  • Developing an efficient MGCR microneedle nanovaccine patch for eliciting Th 1 cellular response against the SARS-CoV-2 infection
    Developing an efficient MGCR microneedle nanovaccine patch for eliciting Th 1 cellular response against the SARS-CoV-2 infection

    Gao A.

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  • Photocurable injectable Janus hydrogel with minimally invasive delivery for all-in-one treatment of gastric perforations and postoperative adhesions
    Photocurable injectable Janus hydrogel with minimally invasive delivery for all-in-one treatment of gastric perforations and postoperative adhesions

    Wu X.

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  • Engineering CAR-T cells for radiohapten capture in imaging and radioimmunotherapy applications
    Engineering CAR-T cells for radiohapten capture in imaging and radioimmunotherapy applications

    Kurtz K.

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  • Upregulated FOXM1 stimulates chondrocyte senescence in Acot12-/-Nudt7-/- double knockout mice
    Upregulated FOXM1 stimulates chondrocyte senescence in Acot12-/-Nudt7-/- double knockout mice

    Song J.

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  • Universal theranostic CRISPR/Cas13a RNA-editing system for glioma
    Universal theranostic CRISPR/Cas13a RNA-editing system for glioma

    Wu Y.

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  • Piezo1 specific deletion in macrophage protects the progression of liver fibrosis in mice
    Piezo1 specific deletion in macrophage protects the progression of liver fibrosis in mice

    Luo S.

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  • Tet1 deficiency exacerbates oxidative stress in acute kidney injury by regulating superoxide dismutase
    Tet1 deficiency exacerbates oxidative stress in acute kidney injury by regulating superoxide dismutase

    Fan Y.

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  • Oral [60]fullerene reduces neuroinflammation to alleviate Parkinson s disease via regulating gut microbiome
    Oral [60]fullerene reduces neuroinflammation to alleviate Parkinson s disease via regulating gut microbiome

    Li X.

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  • Fe(III)-Shikonin supramolecular nanomedicines as immunogenic cell death stimulants and multifunctional immunoadjuvants for tumor vaccination
    Fe(III)-Shikonin supramolecular nanomedicines as immunogenic cell death stimulants and multifunctional immunoadjuvants for tumor vaccination

    Feng W.

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  • Discovery of a novel NAMPT inhibitor that selectively targets NAPRT-deficient EMT-subtype cancer cells and alleviates chemotherapy-induced peripheral neuropathy
    Discovery of a novel NAMPT inhibitor that selectively targets NAPRT-deficient EMT-subtype cancer cells and alleviates chemotherapy-induced peripheral neuropathy

    Kim M.

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  • Systemic delivery of glycosylated-PEG-masked oncolytic virus enhances targeting of antitumor immuno-virotherapy and modulates T and NK cell infiltration
    Systemic delivery of glycosylated-PEG-masked oncolytic virus enhances targeting of antitumor immuno-virotherapy and modulates T and NK cell infiltration

    Liang Y.

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  • Inhalation of acidic nanoparticles prevents doxorubicin cardiotoxicity through improvement of lysosomal function
    Inhalation of acidic nanoparticles prevents doxorubicin cardiotoxicity through improvement of lysosomal function

    Santin Y.

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  • Three-dimensional nanofibrous sponges with aligned architecture and controlled hierarchy regulate neural stem cell fate for spinal cord regeneration
    Three-dimensional nanofibrous sponges with aligned architecture and controlled hierarchy regulate neural stem cell fate for spinal cord regeneration

    Li Z.

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  • Engineering strategies and optimized delivery of exosomes for theranostic application in nerve tissue
    Engineering strategies and optimized delivery of exosomes for theranostic application in nerve tissue

    Li Q.

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  • Secretome of senescent hepatic stellate cells favors malignant transformation from nonalcoholic steatohepatitis-fibrotic progression to hepatocellular carcinoma
    Secretome of senescent hepatic stellate cells favors malignant transformation from nonalcoholic steatohepatitis-fibrotic progression to hepatocellular carcinoma

    Zhou Y.

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  • DNMT1 mediates the disturbed flow-induced endothelial to mesenchymal transition through disrupting ?-alanine and carnosine homeostasis
    DNMT1 mediates the disturbed flow-induced endothelial to mesenchymal transition through disrupting ?-alanine and carnosine homeostasis

    Zhao J.

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