Application of an F0-based genetic assay in adult zebrafish to identify modifier genes of an inherited cardiomyopathy

Yonghe Ding

Intrinsic and extrinsic regulation of rhabdomyolysis susceptibility by Tango2

Euri S. Kim

See[ing] elegance in sensory biology: an interview with Piali Sengupta

Piali Sengupta

Acute frataxin knockdown in induced pluripotent stem cell-derived cardiomyocytes activates a type I interferon response

M. Grazia Cotticelli

Welcoming new Editors

Kirsty M. Hooper

A zebrafish model of combined saposin deficiency identifies acid sphingomyelinase as a potential therapeutic target

Tejia Zhang

First person – Mark Hanson

Optical measurement of gating pore currents in hypokalemic periodic paralysis model cells

Tomoya Kubota

First person – Kevin Zhang

Modifying the approach to cardiomyopathy research

Kirsty M. Hooper

Modeling the effects of genetic- and diet-induced obesity on melanoma progression in zebrafish

Emily Montal

Mechanistic studies in Drosophila and chicken give new insights into functions of DVL1 in dominant Robinow syndrome

Sarah J. Gignac

Let's talk about sex… obesity and melanoma

Kirsty M. Hooper

Pharmacological inhibition of the acetyltransferase Tip60 mitigates myocardial infarction injury

Xinrui Wang

First person – Koray Ütkür

First person – John (Eddie) Edmund La Marca

The loop-tail mouse model displays open and closed caudal neural tube defects

Beatriz Fernández-Santos

First person – Rodanthi Lyraki

FZD2 regulates limb development by mediating β-catenin-dependent and -independent Wnt signaling pathways

Xuming Zhu

Designer pigs for xenogeneic heart transplantation and beyond

Eckhard Wolf

Sphingolipid imbalances inflame the bowel

Kirsty M. Hooper

Activated PI3K delta syndrome 1 mutations cause neutrophilia in zebrafish larvae

Stone Elworthy

NOTCH signalling – a core regulator of bile duct disease?

Anabel Martinez Lyons

DPH1 and DPH2 variants that confer susceptibility to diphthamide deficiency syndrome in human cells and yeast models

Koray Ütkür

A DUSP6 inhibitor suppresses inflammatory cardiac remodeling and improves heart function after myocardial infarction

Zongwang Zhang

The shifting culture of the scientific workforce – a change for women and girls in science

Kirsten C. Sadler

Laforin targets malin to glycogen in Lafora progressive myoclonus epilepsy

Sharmistha Mitra

An automated microscopy workflow to study Shigella–neutrophil interactions and antibiotic efficacy in vivo

Arthur Lensen

In vivo quantitative high-throughput screening for drug discovery and comparative toxicology

Patricia K. Dranchak

Mouse models of fragile X-related disorders

Rob Willemsen