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A randomised controlled trial of the probiotic Bifidobacterium breve BBG-001 in preterm babies to prevent sepsis, necrotising enterocolitis and death: the Probiotics in Preterm infantS (PiPS) trial.
Kate Costeloe,?Ursula Bowler,?Peter Brocklehurst,?Pollyanna HardyPaul Heal
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A randomised controlled trial to assess the clinical effectiveness and cost-effectiveness of alternative treatments to Inhibit VEGF in Age-related choroidal Neovascularisation (IVAN).
Usha Chakravarthy,?Simon P Harding,?Chris A Rogers,?Susan DownesAndrew J Lotery
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A randomised controlled trial to evaluate the impact of a human rights based approach to dementia care in inpatient ward and care home settings.
Peter Kinderman,?Sarah Butchard,?Ashley J Bruen,?Abbie WallNia Goulden
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A randomised placebo-controlled Phase III multicentre trial: low-dose intravenous immunoglobulin treatment for long-standing complex regional pain syndrome (LIPS trial).
Andreas Goebel,?Jatinder Bisla,?Roy Carganillo,?Claire ColeBernhard Frank
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A randomised placebo-controlled trial of oral and topical antibiotics for children with clinically infected eczema in the community: the ChildRen with Eczema, Antibiotic Management (CREAM) study.
Nick A Francis,?Matthew J Ridd,?Emma Thomas-Jones,?Victoria ShepherdChristopher C Butler
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A randomised, double-blind, parallel-group trial to assess mercaptopurine versus placebo to prevent or delay recurrence of Crohn disease following surgical resection (TOPPIC).
Jack Satsangi,?Nicholas A Kennedy,?Craig Mowat,?Ian ArnottCatriona Keerie
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A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients with cystic fibrosis.
Eric WFW Alton,?David K Armstrong,?Deborah Ashby,?Katie J BayfieldDiana Bilton
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A rapid synthesis of the evidence on interventions supporting self-management for people with long-term conditions: PRISMS
Stephanie JC Taylor,?Hilary Pinnock,?Eleni Epiphaniou,?Gemma PearceHannah L Parke
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A realist analysis of hospital patient safety in Wales: applied learning for alternative contexts from a multisite case study.
Andrea Herepath,?Martin Kitchener,?Justin Waring
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A realist informed mixed-methods evaluation of Schwartz Center Rounds in England.
Jill Maben,?Cath Taylor,?Jeremy Dawson,?Mary LeamyImelda McCarthy
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A realist process evaluation of robot-assisted surgery: integration into routine practice and impacts on communication, collaboration and decision-making.
Rebecca Randell,?Stephanie Honey,?Jon Hindmarsh,?Natasha AlvaradoJoanne Greenhalgh
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A revised teaching assistant-led extracurricular physical activity programme for 8- to 10-year-olds: the Action 3:30R feasibility cluster RCT.
Russell Jago,?Byron Tibbitts,?Alice Porter,?Emily SandersonEmma Bird
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A school intervention for 13- to 15-year-olds to prevent dating and relationship violence: the Project Respect pilot cluster RCT.
Rebecca Meiksin,?Jo Crichton,?Matthew Dodd,?Gemma S MorganPippa Williams
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A school-based intervention to increase physical activity levels among 11- to 14-year-old girls: cluster RCT
Deirdre M Harrington,?Melanie J Davies,?Danielle Bodicoat,?Joanna M CharlesYogini V Chudasama
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A scoping study to explore the cost-effectiveness of next-generation sequencing compared with traditional genetic testing for the diagnosis of learning disabilities in children.
Sophie Beale,?Diana Sanderson,?Anna Sanniti,?Yenal DundarAngela Boland
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A self-management programme to reduce falls and improve safe mobility in people with secondary progressive MS: the BRiMS feasibility RCT.
Hilary Gunn,?Jackie Andrade,?Lorna Paul,?Linda MillerSiobhan Creanor
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A study of cellular counting to determine minimum thresholds for adequacy for liquid-based cervical cytology using a survey and counting protocol.
Henry C Kitchener,?Matthew Gittins,?Mina Desai,?John HF SmithGary Cook
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A support package for parents of excessively crying infants: development and feasibility study.
Ian St James-Roberts,?Rosemary Garratt,?Charlotte Powell,?Deborah BamberJaqui Long
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A systematic review and cost-effectiveness analysis of specialist services and adrenaline auto-injectors in anaphylaxis.
N Armstrong,?R Wolff,?G van Mastrigt,?N MartinezAV Hernandez
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A systematic review and economic evaluation of adalimumab and dexamethasone for treating non-infectious intermediate uveitis, posterior uveitis or panuveitis in adults.
Hazel Squires,?Edith Poku,?Inigo Bermejo,?Katy CooperJohn Stevens
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A systematic review and economic evaluation of bisphosphonates for the prevention of fragility fractures.
Sarah Davis,?Marrissa Martyn-St James,?Jean Sanderson,?John StevensEdward Goka
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A systematic review and economic evaluation of diagnostic strategies for Lynch syndrome.
Tristan Snowsill,?Nicola Huxley,?Martin Hoyle,?Tracey Jones-HughesHelen Coelho
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A systematic review and economic evaluation of exercise referral schemes in primary care: a short report.
Fiona Campbell,?Mike Holmes,?Emma Everson-Hock,?Sarah DavisHelen Buckley Woods
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A systematic review and economic evaluation of intraoperative tests [RD-100i one-step nucleic acid amplification (OSNA) system and Metasin test] for detecting sentinel lymph node metastases in breast cancer.
Nicola Huxley,?Tracey Jones-Hughes,?Helen Coelho,?Tristan SnowsillChris Cooper
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A systematic review and economic evaluation of new-generation computed tomography scanners for imaging in coronary artery disease and congenital heart disease: Somatom Definition Flash, Aquilion ONE, Brilliance iCT and Discovery CT750 HD.
M Westwood,?M Al,?L Burgers,?K RedekopS Lhachimi
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A systematic review and economic evaluation of subcutaneous and sublingual allergen immunotherapy in adults and children with seasonal allergic rhinitis.
A Meadows,?B Kaambwa,?N Novielli,?A HuissoonA Fry-Smith
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A Systematic Review and Economic Evaluation of the Use of Tumour Necrosis Factor-Alpha Inhibitors, Adalimumab and Infliximab, for Crohn's Disease.
J Dretzke,?R Edlin,?J Round,?M ConnockC Hulme
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A systematic review and individual patient data meta-analysis of prognostic factors for foot ulceration in people with diabetes: the international research collaboration for the prediction of diabetic foot ulcerations (PODUS).
Fay Crawford,?Genevieve Cezard,?Francesca M Chappell,?Gordon D MurrayJacqueline F Price
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A systematic review and metaethnography to identify how effective, cost-effective, accessible and acceptable self-management support interventions are for men with long-term conditions (SELF-MAN).
Paul Galdas,?Zoe Darwin,?Jennifer Fell,?Lisa KiddPeter Bower
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A systematic review of evidence on malignant spinal metastases: natural history and technologies for identifying patients at high risk of vertebral fracture and spinal cord compression.
P Sutcliffe,?M Connock,?D Shyangdan,?R CourtN-B Kandala